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肝硬化、肝癌病人血清β2微球蛋白测定的临床意义
CLINICAL SIGNIFICANCE OF β2-MICROGLOBULIN MEASUREMENT IN PATIENTS WITH CIRRHOSIS AND HEPATIC CARCINOMA (ABSTRACT)
【摘要】 本文采用放免法检测了经临床确诊为肝硬化36例、原发性肝癌34例的血清β2-微球蛋白含量,结果阳性率分别为77.7%及79.4%。提示β2-微球蛋白检测对肝硬化、原发性肝癌无鉴别意义;对原发性肝癌β2-微球蛋白敏感性高,特异性差,须结合其他的有关血清学检测结果综合判断。
【Abstract】 The serum concentration of β2-microglobulin in 36 patients withcirrhosis of the liver and 34 patients with primary hepatic carcinomawas measured by radio-immuno-assay (RIA), the positive rate being77.7% and 79.4 % respectively. These results suggest that β2-microglobu-lin bears no significance in differeintiation of cirrhosis and carcinoma.β2-microglobulin had a high sensitivity but a low specificity in primaryhepatic carcinoma. Therefore the diagnosis should be considered byother seralogical data.
【关键词】 β2微球蛋白;
肝硬化;
原发性肝癌;
【Key words】 β2-microglobulin(β2M); cirrhosis of the liver; primary hepatic carcinoma;
【Key words】 β2-microglobulin(β2M); cirrhosis of the liver; primary hepatic carcinoma;
- 【文献出处】 大连医学院学报 , 编辑部邮箱 ,1990年03期
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