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不育男性精浆中γ-谷氨酰转肽酶的研究

A STUDY ON THE ACTIVITY OF γ-GLUTAMYL TRANSPEPTIDASE IN SEMINAL PLASMA FROM INFERTILE MAN

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【作者】 李陆英付淝韩秀雯初燕侠崔向东

【Author】 Li Luying, et al Department of Biochemistry

【机构】 青岛医学院生物化学教研室青岛市南区第一医院不育诊所青岛医学院生物化学教研室

【摘要】 用重氮试剂比色法对92例不育男性及20例正常生育男性精浆中γ-谷氨酰转肽酶(γ-GT)活力进行测定.结果表明,不育组γ-GT酶活力为204 966±103 330活力单位/L,明显高于正常生育组161 556±29 074活力单位/L(P<0.01).γ-GT酶活力与精子密度呈正相关(n=72,r=0.491,P<0.01);与精子存活率亦呈正相关(n=60,r=0.3192,P<0.05);与精子畸形率无相关性存在.

【Abstract】 The activity of γ-glutamyl transpeptidase (γ-GT) in seminal plasma from 92 cases of infertile and 20 cases of normal fertile men was studied with azareagent colorimetry method. The mean value of seminal γ-GT was 204 966±103 330 unit/L in the infertile group. It showed a marked increase in comparison with the normal group (161 556±29 074 unit/L, P<0.01). The positive correlation was found between the activity of γ-GT and the density of sperms (n=72, γ=0.491, P<0.01). Positive correlation was also found between the activity of γ-GT and the survival rate of sperms (n=60, r=0.3192, P<0.05). No correlation was found between the activity of γ-GT and rate of sperm aberration.

【关键词】 不育症男性精液γ-谷氨酰转移酶
【Key words】 InfertilitymaleSemenγ-glutamyl transferase
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