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FAM方案治疗晚期腺癌的临床观察

FAM RECIMEN IN THE TREATMENT OF ADVANCED ADENOCARC I NOMA

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【作者】 秦凤展; 张家驹; 谈承芸; 郑荣生; 丁永为; 毕明宏; 王子安; 孙惠娟;

【Author】 QIN Feng-zhan ZHANG Jia-ju TAN Cheng-yun ZHENG Rong-sheng DING Yong-wei BI Ming-hong WANG Zhi-an SUN Hui-juan(Department of Chemotherapy, Affiliated Hospital of Bengbu Medical College,Anhui, 233000)

【机构】 安徽省蚌埠医学院附属医院肿瘤内科; 安徽省蚌埠医学院附属医院肿瘤内科;

【摘要】 本文报道用调整后的FAM方案治疗53例晚期腺癌,获得疗效完全缓解3例,部分缓解17例,总有效率为37.7%。其中以乳腺癌和胃癌的疗效最佳,有效率分别为66.7%和48.4%,肺癌和结直肠癌的疗效均差。本方案的主要毒性作用为胃肠道反应及骨髓抑制,但多属I~Ⅱ度,患者均能耐受。

【Abstract】 5 3 advanced adenocarcinoma were treated with adjusted FAM(5-Fluorouracil , Adriamycin, Mitomycin), regimen and the overall response rate (RR) was 37.7% ( CR3, and PRl7). The best result was seen in mammary and gastric carcinoma (RR= 66.7% and 48.4% respectively), but the response rates for lung and Colo-rectal carcinoma were poor.The major toxic side effects were gestrointestinal tract and myelosuppfession , but the great majority was limited to 1-11 grade, and patients were tolerable.

  • 【文献出处】 癌症 ,Chinese Journal of Cancer , 编辑部邮箱 ,1990年03期
  • 【被引频次】5
  • 【下载频次】11
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