【摘要】 用 Q-开关红宝石激光制作家兔眼内出血模型共39只兔58只眼,造模后视网膜电图(ERG)振幅明显下降。经活血化瘀复方——眼底Ⅲ号治疗3周,ERG 振幅明显恢复,a 波最大及最终恢复均为33%,b 波最大及最终恢复分别为34%、28%,比尿激酶组、空白对照组恢复程度高且稳定持久(P<0.05)。更多还原

【Abstract】 Experiments were conducted in chinchilla rabbits to determine the effect of Huoxue-Huayu (promote blood circulation to remove blood stasis)on the electroretinogram(ERG).An animal model of intraocular hemorrhage was established by radiating of Q-switched ruby laser in 58 eyes of 39 rabbits.After laser radiation,the amplitudes of ERGs of the animal eyes were remarkably reduced. The animals were randomly divided into 3 groups.One group was the control group without any treatment.The other two groups were treated with Yandi Decoction Ⅲ(眼底Ⅲ号,a composite prescription of Huoxue-Huayu)and urokinase respectively for 3 weeks.The depressed ERGs in the Yandi Decoction Ⅲ treated group showed remarkable recovery during 6 weeks after starting treatment,comparing with that in the control group and the urokiaase treated group(P<0.05), Finally,the 33% of the lost amplitude of a-wave and 28% of b-wave in the Yandi Decoction Ⅲ treated group were recovered.The mechanism of ERG recovery in the Huoxue-Huayu therapy was also preliminarily discussed in the paper.更多还原