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阳虚证患者遗传学特征探讨

Genetic Characteristics in Yang(阳)Deficieney Patients

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【作者】 冯栋年; 刘燕玲; 张新; 郝敬玲; 罗伟; 陈至惠; 陈世敬; 王慕虹; 徐长桂;

【Author】 Feng Dongnian Liu Yanling Fourth People’s Hospital,Xuzhou

【机构】 江苏省徐州市第四人民医院; 江苏省徐州市第四人民医院; 江苏省中医研究所;

【摘要】 从遗传学角度出发,对50例阳虚证患者,230名健康人进行了白细胞抗原(HLA)检测,同时对50例阳虚证患者及60名健康人作了 Rohrer 指数及肋弓角测定。结果,阳虚组 HLA-B5、Cw3、A9频率分布较健康人为低,两组差异均有显著性(P<0.05~0.01)。推测阳虚证的发生与其免疫调控紊乱有关。Rohrer 指数>1.50者,以阳虚组为多(P<0.01),肋弓角测定阳虚组为80.6°±14.35°,健康组为69.5°±11.83°(P<0.01),均示阳虚组体胖者居多。

【Abstract】 With regard to genetic aspects,the authors determined the HLA typing in 50 cases of Yang deficiency(YD)-syndrome and 230 healthy controls.Rohrer index and costae arcuarial angie were also measured in 50 cases of YD syndrome and 60 healthy controls.The results showed that the distributional frequencies of HLA-B5 P<0.05),CW3(P<0.01)and A9(P<0.05)in YD were signifi. cantly lower than those in normal controls.It reflected the genetic characteristics of YD syndrome indirectly.The YD patients had higher Rohrer index(more than 1.50)than normal controls.The costae arcuarial angle of YD group was 80±14.35 degree(mean±SD),and that of normal controls was 69.5±11.83 degree.These indicated that fattiness was more often seen in the YD group.

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