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益气养阴活血治法的抗衰老机理研究——Ⅲ、“气血通”对老年大鼠组织细胞核体外转录活性的影响

The Effects of a Chinese Traditional Herb Drug on RNA Synthesis in Isolated Nuclei and Chromatins of Aging Rats

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【作者】 杜延顺张宗玉毛腾敏

【Author】 Du Yanshuan et al (Department of Biochemistry, Beijing Medical University)

【机构】 北京医科大学生化教研室北京医科大学中西医结合教研室

【摘要】 用益气养阴活血中药方剂“气血通”(人参、丹参、沙参等八味中药组成)掺入饲料喂养大鼠,可增加老年动物存活率,并提高老年大鼠肝、脾、脑、肾细胞核体外转录活性。

【Abstract】 Old rats (25 months of age) were divided into control and experimental groups, and xperimental group was fed with a diet containing 1 % Qixuetong (a Chinese herb compound drug)for 100 day.RNA synthesis in nuclei of brain,liver, spleen and kidney of the drug-eating group were determined and found to be respectively about 16% ,51%, 38% and 47%,, It was higher than those of control group which was in same age but without Qixuetong diet. Meanwhile the mortality of the drug-eating group was 50%(12/24), and that of the control group was 25%(11/44). These results suggest that Qixuetong has some anti-aging effect.

【关键词】 QixuetongRNA synthesisNucleiChromatinMortality.
【Key words】 QixuetongRNA synthesisNucleiChromatinMortality.
【基金】 国家自然科学基金资助课题
  • 【文献出处】 中药药理与临床 ,Pharmacology and Clinics of Chinese Materia Medica , 编辑部邮箱 ,1989年05期
  • 【下载频次】41
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