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沙棘浓缩果汁对实验性肝损伤的保护作用

Protection Against Experimental Hepatic Injury by Condensed Fruit-Juice of-Hippophae Rhemnoides L.(HR)

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【作者】 程体娟曹中吉马征蓉张培棪

【Author】 Chen Tijuan, Cao Zhong, Ma Zhengrong, Zhang Peyan (Dept pharmacology, Lanzhou Medical College, Lanzhou)

【机构】 兰州医学院药理室兰州医学院药学系兰州医学院药理室 兰州兰州 88届毕业生兰州

【摘要】 沙棘浓缩果汁对CCl4及扑热息痛(AAP)损伤肝丙二醛(MDA)的增高有明显抑制作用,并能显著降低CCl4中毒小鼠SGPT活力,对抗AAP中毒小鼠肝谷胱甘肽(GSH)的耗竭,延长小鼠睡眠时间。

【Abstract】 Protection by condensed fruit juice of HR against hepatotoxicity induced by CCl4 and acetaminophen (AAP) was studied in this paper, It was found that condensed fruit juice of HR inhibited markedly MDA formation of liver induced by CCl4 and AAP, decreased sigaificantly SGPT levels induced by CCl-44 and blocked depletion of GSH damaged liver induced by AAP. ID addition, condensed fruit juice of HR prolonged sleeping time in mice.

  • 【文献出处】 中药药理与临床 ,Pharmacology and Clinics of Chinese Materia Medica , 编辑部邮箱 ,1989年02期
  • 【被引频次】6
  • 【下载频次】81
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