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粮食提取物的致病研究—对恒河猴的致大骨节病试验

Experimental study of grain abstract on causing Kaschin-Beck disease in monkeys

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【作者】 张宏绪李连群刘锦先孙奎张桂芹王殿芝张爱敏王书建姚奎勤于全荣刘西汉王金木

【Author】 Kaschin-Beck disease Institute of Heil- ongJiang Province Zhang Hongxu, Li Lianqun, Liu Jinxian, Sunkui, Zhang Quqin, and Wang Dianzhi Endemic Institute of Luo Yang

【机构】 黑龙江省大骨节病研究所河南省洛阳地方病防治研究所河南省洛阳地方病防治研究所 哈尔滨医科大学

【摘要】 本实验用大骨节病活跃病区玉米的提取物挥发胺(盐),喂饲恒河猴,结果见到受试猴肢体骺板软骨和关节软骨深层出现软骨坏死,这与人类大骨节病的改变相同,为病因学研究提供了新线索。

【Abstract】 The experimental study in monkeys fed with abstract, a kind of evaporable and basophil matter with nitrogen, from grain of active endemic area was reported for the first time. Necrosis and proeiferation of cartilage in the hypertrophyc zone of the growth plate and the deep layer of articular cartilage were seen in the experimental. The lesions of the cartilage combined with roentgenelogic changes in these monkeys were considered similar to these in human Kaschin-Beck disease. The experiment gave a new clue to study of cause of Kaschin-Beck disease.

【关键词】 大骨节病挥发胺动物试验
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