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A群流脑多糖菌苗婴幼儿免疫程序及免疫效果持久性研究

OBSERVATION OF IMMUNIZATION SCHEDULE AND RES1STANCE OF POLYSACCHARIDE VACCINE OF GROUP A NEISSERIA

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【作者】 钟腾祥潘汉中周健先曾玉英王定明陈策林永根赖培新田虹吴铁菊李照毅付春霞

【Author】 Zhong TengXiang et al., HEALTH AND PREVENTION CUIZEOU etc.

【机构】 贵州省卫生防疫站譐义地区卫生防疫站贵州省卫生防疫站

【摘要】 本文报告了我省以每针皮下注射流脑多糖菌苗50μg,用不同基免方法对6月龄~5岁儿童进行免疫后,连续3年的血清A群流脑杀菌抗体的动态观察。

【Abstract】 After the children of six-month to five-year old age group were vaccinated primarily with one dose (50ug) and two- dose (at three months interval of polysaccharide vaccine of group A Neisseria meningitidis, the serological results of three-year observation showed the level of the antibody on primary immunization rises one month later, and drops rapidly three months later. At that time, the level of the antibody rise after giving one dose more again. No matter wether one dose or two-dose primary immunization is given, the level of the antibody drops to the level before giving primary immunization one year later. But the level of the antibody would exceed several times after giving a booster dose and one year later, maitains the level of primory immunization one month later.

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