【摘要】 本文对69例胃粘膜活检标本(胃炎,胃癌伴肠化生),应用免疫组化及组织化学方法观察两类病例肠化生血型抗原的分布,并探讨肠化生与血型物质消长的关系。结果表明胃炎及胃癌伴肠化生两者血型物质消长无明显差异。肠化类型与血型物质比较,完全性与不完全性结肠型的血型物质消长之比,后者血型物质消失多于前者故P<0.01有非常显著意义。本文结果提示,不完全性结肠型肠化生与不完全性小肠型肠化生血型物质的消失以及不完全性结肠型与完全性结肠型肠化生血型物质消失情况分析说明不完全性结肠型肠化生的去分化现象较其他型肠化生明显。本研究支持一些学者的报道,认为不完全性结肠型肠化生与胃癌关系密切。更多还原

【Abstract】 The distributions of the blood group antigens were observed by mucin andimmunohistochemical methods both in the intestinal metaplasia with chronicgastritis and gastric cancer. The relationship between the A.B.H.blood groupantigens and different types of intestinal metaplasia was disccused. The result showed that there is no signifcant difference in expressions of blood-group antigens between the intestinal metaplasia with chronic gastritis and gasriccancers. Comparing the expressions of blood group antigens with different typesof intestinal metaplasia. The decrease of the expression of blood group antigens inincomplete colonie metaplasia is much more significant than that of complete clonicmetaplsia(P<0.01). The result of this study suggested that the degree of dedifferen-tiation of incomplete colonic metapasia is much more significant than other typesof metaplasia. This result supported someauthers’ idea that the incomplete coloniemetapsia is closely related to the gastric cancer.更多还原