【摘要】 本文对血管免疫母细胞性淋巴结病的临床和病理所见作了介绍。年龄5～67岁,平均43岁。男性8例,女性6例,临床表现与恶性淋巴瘤相似,都有淋巴结病。发热10例,肝脏肿大7例,脾脏肿大7例,严重贫血5例及皮肤疹2例。4例分别于6～12个月死亡,1例尸检证实已发展为免疫母细胞肉瘤。病理组织学上主要表现是淋巴结的广泛破坏,丰富的小血管及内皮细胞的增生,显著的免疫母细胞、前浆及浆细胞的增生和不同程度的嗜酸性粒细胞浸润。更多还原

【Abstract】 The clinical and pathologic findings ih 14 patients with angioimmunoblastic lymphadenopathy(AILD)are presented.The patients’ ages ranged from 5 to 67 yearswith a median age of 43 years. This series included 8 men and 6 women. Theclinical presentation is suggested as malignant lympboma. All of the patients hadlymphadenopathy, 10 patients had fever, 7 had hepatomegaly, 7 splenomegaly, 5severe anemia and skin rashes in two. Hypergammaglobulinemia was found in 5of 6 patients. Four patients was die of disease rapidly (6 to 12 month) afterdiagnosis. Moreover, immunoblastic sarcoma was appeared in autopsy. The main fea-tures of pathology are: extensive alteration in the nodal architecture, abundantsmall vessels with hyperplasia endothelium, pronounced proliferation of immuno-blasts and pre-plasmacytes and plasmacytes with varied infiltration of acidocytes.更多还原