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DCC法测定乳腺癌雌激素受体方法的研讨
AN INVESTIGATION OF DEXTRAN-COATED CHARCOAL ASSAY FOR ESTROGEN RECEPTOR IN BREAST CANCER
【摘要】 用DCC多点法和单点饱和法对32例乳腺癌标本做ER受体测定,并对两法做了仔细比较,发现它们的结果有相关性。用统计学处理比较两者之间的差别,发现:用秩和检验法得P>0.1,用配对t检验法得P>0.5,说明二者之间无显著差别。作者认为单点饱和法的优点是方法简便,需用瘤体组织少,成本低廉,因此认为DCC单点法是可取的。
【Abstract】 A study on single-point dextran-coated charcoal method and multipoint Scatchard analysis for estrogen receptor assay in breast cancer was performed in 32 cases.Their results were carefully compared. It has been shown that the Single-pointassay for estrogen receptor has good correlation with values obtained from mul-tipoint Scatchard analysis in this present study. Stastically. there were no signi-ficant difference between the results of two methods (P>0.1 in rank sum test andP>0.5 in paired t-test). Advantages of the single-point assay are to simplifythe procedure, to reduce amount of tissue required and cost per assay. The authorstherefore, believe it is unnecessary to carry-out Scatchard plot analysis for everycase.
- 【文献出处】 肿瘤防治研究 ,Cancer Research on Prevention and Treatment , 编辑部邮箱 ,1989年01期
- 【被引频次】4
- 【下载频次】25