【摘要】 本文采用F₃₄₄雌性大鼠。皮下注射雌二醇,30天后诱发出泌乳素腺瘤。经血管内灌注墨汁,连续切片,观察血管构筑。发现视交叉及视束内侧部的毛细血管僵直、细小、密度降低、软膜下血管瘀血。表明垂体瘤发生后,视交叉及视束内侧部供血受阻、循环障碍,继发水肿及代谢障碍,是垂体瘤直接压迫视交叉之前,造成视野功能障碍的基础。更多还原

【Abstract】 Experimental pituitary tumors were induced 30 days after the injection of estrodiol hypodermically in 54 F544 female rats.The mean weight of the tumors was 57.2564±1.3mg. Those tumors were prolactin adenomas verified by light and electronic microscopy. The blood vessles of pituitary, optic chiasma and tract, and hypothalamus were injected with Chinese ink, Pathological examination found that blood sinusoids within the pituitary tumor.The capillaries became stiffened and slender, decreased in number and the pial blood vessels were engorged and obstructed over the medial aspect of optic chiasma and optic tract. Thus might subsequent edema and metabolic disturbance of medial side of optic chiasma and optic tract. These were the bases responsible for the dysfunction of visual acuity and visual field.更多还原