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成骨肉瘤放化综合治疗——附18例分析

COMBINATION OF RADIOTHERAPY AND CHEMOTHERAPY FOR OSTEOGENIC SARCOMA

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【作者】 吴敬亮胡景铃罗鹏飞邵培坚陈乃楹陈应瑞周泽健

【Author】 Wu Jingliang People’s Hospital of Guangdong Province

【机构】 广东省人民医院广东省人民医院

【摘要】 <正> 成骨肉瘤的治疗,目前仍以截肢为主要手段,疗效欠佳。为探索对本病治疗的新方法,从1986年1月至1989年2月,按拟定放化综合治疗方案治疗了18例,现作一小结。

【Abstract】 Eighteen pa’tients with pathologically proved osteogenic sarcoma treated with local radiation and arterial perfusion of cytotoxic agents followed by a half year of systemic chemotherapy are reported. Prior to the institution of this regimen, four patients had already had pulmonary metastases and three were complicated by pathologic fracture at the primary site.Follow-up periods ranged from 4-38 months (mean 14.53 months) . The survival rate was 77% (14/18).Four of these 18 patients died 15-27 months (mean 22 months) after treatment. No local recurrence or other complications were observed in these patients.This study suggests synergistic action of radiation and cytotoxic agents against this tumor.

  • 【文献出处】 中国放射肿瘤学 ,Chinese Journal of Radiation Oncology , 编辑部邮箱 ,1989年04期
  • 【被引频次】1
  • 【下载频次】20
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