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树参叶抗心律失常作用的研究
Studies on Antiarrhythmic Effects of the Leaves of Dendropanax chevalieri (Vig.) Merr. et Chun.
【摘要】 树参叶水提物灌胃给药对乌头碱、CaCl2诱发的小鼠心律失常和BaCl2所致的大鼠心律失常均有明显的保护作用;静注给药能显著缩短肾上腺素诱发的麻醉兔心律失常的持续时间;还能明显推迟哇巴因性豚鼠离体心脏心律失常和心电消失的出现。
【Abstract】 Aqueous extract of the leaves of Dendropanax chevalieri (DC), administrated orally, showed prominent protective effect against arrhythmias induced by iv aconitine CaCl2(120mg/kg)in mice and BaCl2 (4mg/kg) in rats. In anesthetized rabbits, the duration of arrhythmia elicited by iv Adr 75μg/kg was markedly shortened by iv DC 0.4g/kg. It might also obviously delay the onset of arrhythmias and cardiac electricity disappearance evoked by ouabain perfusing consistently into isolated guinea-pig hearts.
- 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,1989年06期
- 【被引频次】19
- 【下载频次】143