【摘要】 通过异烟肼栓与异烟肼片在兔体内血药浓度的测定及动力学参数的计算,结果表明,异烟肼栓的吸收速度常数、峰值浓度、血浓一时间曲线下面积明显高于异烟肼片,达峰时间较异烟肼片快。更多还原

【Abstract】 The isoniazide plasma concentration afteradministration of suppositories was comparedwith that of tablets in rabbits in addition tothe kinetic parameters.The results it wasshowned that the absorption rate wasconst-ant and maximun plasma drug concentrationand AUC of suppositories were considerablyhigher than those of tablets,while theraising time up to the peak was shorterthan the former.更多还原