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肺心病患者血浆心钠素测定及其临床意义

DETERMINATION OF PLASMA CARDIONATRIN IN CHRONIC COR PULMONALE PATIENTS AND ITS CLINICAL SIGNIFICANCE

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【作者】 傅海香; 李胜岐; 张跃祥; 张怀宝;

【Author】 Fu Haixiang, et al (Dept. of Internal Medicine, The Third Affiliated Hospital)

【机构】 中国医科大学附属第二医院内科; 中国医科大学附属第二医院同位素室; 鞍钢铁东医院;

【摘要】 利用放射免疫方法测定44例肺心病患者及30例健康人血浆心钠素(ANP)的含量,分别为663.75±75.63pg/ml,382.91±197.74pg/ml)。两组之间有显著差异(P<0.01)。而且血浆ANP的变化与肺心病心衰的严重程度有关,心衷越重,血浆ANP含量越高;随病情好转血浆ANP含量逐渐下降。因此,从血浆的ANP变化,可以判定肺心病的病情及预后。

【Abstract】 The concentrations of plasma cardionatrin in 44 cases with chronic cor pulmonale and 30 healthy subject were determined by radioimmunoassay. It was found that the concentration of plasma cardionatrin was 382.91±197.74 pg/ml in the normal, and 663.75±75.63 pg/ml in chronic cor pulmonale. The results showed that the concentration of plasma cardionatrin in patients with chronic cor pulmonale was obviously higher than that in the healthy, the more severe the cases with heart failure, the higher the concentration of plasma cardionatrin (P<0.01). The measure of plasma cardionatrin is more valuable not only for observing the patient’s state but also for the patient’s prognosis.

【关键词】 肺心病; 心钠素;
【Key words】 chronic cor pulmonale; cardionatrin;
  • 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,1989年06期
  • 【被引频次】6
  • 【下载频次】9
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