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涎腺粘液表皮样癌的临床病理及免疫组织化学观察

CLINICOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL OBSERVATION OF MUCOEPIDERMOID CARCINOMA OF SALIVARY GLAND

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【作者】 王兆元; 张莹; 曲恒春;

【Author】 Wang Zhaoyuan, et al (Department of Oral pathology)

【机构】 中国医科大学口腔医学系病理教研室; 中国医科大学肿瘤研究所;

【摘要】 本文通过涎腺粘液表皮样癌67例临床病理观察和37例角蛋白-PAS-A.B,免疫组织化学检测,认为本病多见于成年女性。小涎腺中腭腺为其好发部位。常无自觉症状,主要表现为局部结节性肿块。易复发,可发生局部淋巴结转移。免疫组化染色对其临床病理分型及生物学特性的判断有所帮助,并支持本病起源于涎腺闰管贮备细胞的观点。

【Abstract】 Clinicopathological observation of 67 cases of mucoepidermoid carcinoma (MEC) and keratin-mucin immunohistcchemical determination of 37 cases of MEC were completed. In the autor’s opinion, the tumor cecured mainly in the adult females. palat gland was the most predisposing position for MEC cecurring in small salivary gland, often no symptom. The manifestation was mainly local nodular mass. It tended to recur. Metastases in local lymph node could take place occasionally.MEC could be divided into two types: the high and low differentiated. The result of the observation supported that MEC originated from the storage of cells in intercalary duct of salivary gland.

【关键词】 涎腺; 闰管; 粘液表皮样癌;
【Key words】 salivary gland; intercalary duct; muccepidermoid carcinoma;
  • 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,1989年04期
  • 【被引频次】2
  • 【下载频次】27
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