【摘要】 <正> 银耳多糖和木耳多糖具有抗炎症、抗溃疡、保护造血细胞和缓解四氯化碳引起肝细胞损伤等多种活性。银耳具有滋阴生津、治虚热口渴作用,提示该品对糖尿病可能有效。本文探讨了银耳多糖和木耳多糖对小鼠实验性高血糖的防治作用。更多还原

【Abstract】 An experimental diabetic model was induced by vein injection of alloxan monohydrate (100mg/kg). Polysaccharides, which were isolated from Tremella fuciformis Berk and Auricularia auricula, (?)administered po 4h prior to alloxan, were able to decrease blood glucose concentration in mice from 440mg% of the con trol to 245mg% and from 591mg% to 409mg% respectively, at 72h after the injection of alloxan. The oral glucose tolerance test showed that the curves were markedly reduced in the mice treated with the drugs.The blood glucose levels in normal mice and alloxan-induced diabetic mice were significantly reduced by the polysaccharides. The effect of the drugs was most obvious in 4-7h after administration of the polysaccharides. The results suggest that the polysaccharides from Tremella fuciformis Berk and Auricularia auricula might have a cytoprotection effect on cells of pancreatic islets in mice and treatment effect on artificial diabetes.更多还原