【摘要】 本文对61例腹部手术患者连续监测血浆 C-反应蛋白(CRP)和 AT-Ⅲ.发现感染、休克和手术都可使 CRP 升高,AT-Ⅲ:Ag 和 AT-Ⅲ:C 降低.若术后无感染或术前感染被控制,术后 CRP 会迅速降低。第11天接近正常;AT-Ⅲ:Ag 和 AT-Ⅲ:C会迅速升高,第8天接近正常.若术后有感染或术前感染未很好控制,术后 CRP 降低缓慢或降低后再升高:AT-Ⅲ:Ag 和 AT-Ⅲ:C 回升缓慢.严重腹内感染发生 MOF及死亡患者,AT-Ⅲ水平则持续低于正常值的60%.提示手术前后监测 CRP 和 AT-Ⅲ有助于早期发现感染,休克、MOF 和观察疗效,预后.但 CRP 和 AT-Ⅲ受肝功的一定影响.更多还原

【Abstract】 61 patients,before and after abdominal operation,were monitored for plasma CRP and AT-Ⅲ.We found that infection,shock and operation could cause CRP to increase, and AT-Ⅲ:Ag and AT-Ⅲ:C to decrease.If without post-operativc infection or the post-operative infection could bc controlled,CRP would decrease rapidly after operation and close with the normal value by the 11th post-operative day;AT-Ⅲ:C would increase rapidly,and close with the normal value by the 8th post-operative day.If there was post-operative infection or the post-operative infection was not well-controlled,CRP would decrease slowly or re-increase after decrcase;AT-Ⅲ:Ag and AT-Ⅲ:C would have a slow pick-up.In patients whose severe abdominal infection causing MOF and death, AT-Ⅲ.level was continously under 60% of normal value.This shows that pre-and post-operative CRP and AT-Ⅲ surviellance may help us to find out infection,shock and MOF at an early stage and foresee the curative effect and prognosis.But liver functionhas some certain influence on CRP and AT-Ⅲ.更多还原