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16个民族21个群体HLA遗传距离分析

An analysis of genetic distance among 21 populations in 16 nationalities

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【摘要】 收集整理了国内壮、瑶、侗、苗、京、羌、鄂伦春、朝鲜、藏及东乡等15个少数民族和6个汉族群体的HLA基因频率资料,用Nei氏法计算出他们之间的遗传距离,并根据遗传距离按Sneath和Sokal氏聚类原则绘制出系统树。结果发现这些人群之间的遗传距离和系统树所表示的血缘关系与人类学家及历史学家研究的结果基本上一致。

【Abstract】 The genetic distance among 15 national minories (Zhuang, Yiao, Dong, Li, Mongolian, Hasake, Uysur, Jing, Qiang, Olunchun, Zhaoxian, Zang, Dongxiang) and 6 populations living in Hainan, Guangxi, Sichuang, Shanghai, Beijing, and Shenyang was computed with Nei’s method (1978). The HLA gene frequency data were used. A phylogenetie tree of 21 populations was constructed on the basis of genetic distance with the unweighted pair-group method of clustering by Sneath and Sokal (1973).The results show that the phylogenetic relationships revealed in this study agree fundamentally with the results from historical cad anthropological studies.

【关键词】 HLA; 人类群体遗传学; 遗传距离;
【Key words】 HLA; genetic distance; human population genetics;
  • 【文献出处】 右江民族医学院学报 ,Journal of Youjiang Medical College For Nationalities , 编辑部邮箱 ,1989年03期
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