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碳酸锂治疗药源性白细胞减少症的临床研究

Clinical studies of treating drug-induced leukopenia with lithium carbonate

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【作者】 鲁德明马洪春顾佩华江开达

【Author】 LU De-Ming, MA Hong-Chun, GU Pei-Hua (The second People’s Hospital of Yangzhou,Yangzhou 225002)JIANG Kai-Da (Dept of Psychiatry, Shanghai Medical University, Shanghai 200030)

【机构】 扬州市第二人民医院上海医科大学精神医学教研室 扬州 225002扬州 225002上海 200030

【摘要】 32例用抗精神病药物导致的白细胞减少症,在继服原药物同时,口服碳酸锂0.75g/d,升白细胞效果明显,未见不良反应。其中10例与利血生合并维生素B4进行自身前后对照,结果表明碳酸锂升白细胞效果明显优于利血生合并维生素B4,再次证实了碳酸锂有显著的升白细胞作用,值得推广应用。

【Abstract】 32 patients of drug-induced leukopenia induced by antipsychotropics received lithium carbonate orally 0.75 g daily without suspending their original medication.A remarkable rising of leucocytes was observed and devoided from any side effects. Among them 10 patients had leucogen and vitamin B4 beforehand and then turned into lithium carbonate. As the number of WBC count concerned, the latter is definitely superior than the former. Under such circumstances, therefore, lithium carbonate is highly recommended.

【关键词】 碳酸锂白细胞减少症腺嘌呤
【Key words】 lithium carbonateleukopeniaadenine
  • 【被引频次】3
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