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用Diels-Alder反应合成蒽环酮
The Synthesis of Anthracyclinofte by the Diels-Alder Reaction
【摘要】 报道了以呋喃和顺丁烯二酸酐为原料,主要通过Diels-Alder反应合成蒽环酮2-乙酰基-5,12-二乙酰氧基-1,2,3,4-四氢-6,11-并四苯醌的路线,总产率达15%左右。用红外光谱,~1H核磁共振谱和质谱表征合成产物。
【Abstract】 This paper reported the synthesis of anthracyclinone 2-acetyl-5 12-diacetoxy-l,2,3,4-tetrahydro-6,11-naphthacenequinone mainly by the Diels-Alder reaction with an overall yield of 15%, starting from furan and maleic anhydride. The structure of the products were characterised by IR,’HNMR and MS.
【关键词】 Diels-Alder反应;
蒽环酮;
2-乙酰基-5;
12-二乙酰氧基-1,2,3,4-四氢;
【Key words】 Diel-Alder Reaction; Anthracyclinone; 2-Acetyl- 5-12-diacetoxy-1; 2; 3; 4-tetrahydro 6-ll; naphthaceaequinone.;
【Key words】 Diel-Alder Reaction; Anthracyclinone; 2-Acetyl- 5-12-diacetoxy-1; 2; 3; 4-tetrahydro 6-ll; naphthaceaequinone.;
【基金】 国家教育委员会基金
- 【文献出处】 厦门大学学报(自然科学版) ,Journal of Xiamen University(Natural Science) , 编辑部邮箱 ,1989年04期
- 【被引频次】1
- 【下载频次】123