【摘要】 抗生素861-A是玫瑰皮黄链霉菌淡色变种(Strepiomyces roseoalutaceus var.pallidus)产生的抗生素复合物的主要组份,有广谱抗菌活性,对小麦赤霉病有良好的防治效果。以快原子轰击质谱和色谱-质谱联用为主,结合各种化学和波谱方法,对861-A及其降解产物进行结构分析,证明了861-A与链丝菌素F同质,为链丝菌素F的化学结构提供了进一步的证据。更多还原

【Abstract】 Antibiotic 861-A is a major component of antibiotic 861 complex produced by Streptomyces roseoalutaceus var. pallidus, which exhibits a broad antibacterial spectrum and the prevention of wheat scab——one of the major wheat disease in China.The chemical structures of 861-A and its hydrolysates have been identified with FAB-MS and GC/MS as well as comparison in spectroscopic characteristics of IR, ~1H NMR, FAB-MS and TLC of 861-A with that of reference compound Streptothricin F. It is demonstrated that antibiotic 861-A and Streptothricin F are identical. An additional testmony has been offered for the structure of Streptothricin F.更多还原