节点文献

氯化镍对小鼠睾丸影响的研究

Toxic Effects of Nickel Chloride on Testis in Mice

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 李佳慧王兴邦王秀玲刚葆琪

【Author】 Li Jiahui, et al. (Harbin Medical University, School of Public Health)

【机构】 哈尔滨医科大学哈尔滨医科大学

【摘要】 氯化镍可引起小鼠精子数减少、活动能降低及畸形率增高。电镜下看到支持细胞受损严重,精原细胞、精母细胞、精细胞及精子亦均受到不同程度的损害。

【Abstract】 Nickel chloride ( NiCl2. 6H2O ) was administered intraperitoneally to male mice. As indices for reproductive toxicity of water soluble nickel salts in male the counting, .motility and mor phological changes of sperm, primary spermatocyte chromosome aberration, and testicular histo pathology and ultrastructure were observed. The fesults showed that the sperm count and motility were decreased. mprphological abnormality rate of sperm was increased. Under electron micros cope observation Sertoli’s cells was severely damaged, spermatogonia, speraatocytes, spermatids and spermatozoa were also damaged to different extent.

【关键词】 生殖毒性超微结构
【Key words】 Nickel ChlorideReproductive toxicityUltrastructure.
  • 【文献出处】 卫生毒理学杂志 ,Journal of Health Toxicology , 编辑部邮箱 ,1989年04期
  • 【被引频次】29
  • 【下载频次】102
节点文献中: 

本文链接的文献网络图示:

本文的引文网络