【摘要】 用免疫毒理学的方法研究甲基毒死蜱的亚急性和亚慢性染毒对小鼠的免度效应。结果表明,甲基毒死蜱在1/500LD₅₀（2.3 mg/kg）时可对机体胸腺指数、巨噬细胞吞噬功能和外周血T淋巴细胞数产生影响;1/100LD₅₀（1.19mg/kg）为最大无作用剂量。更多还原

【Abstract】 The immunotoxicty of Chlorpyrifos-methyl was studied in mice.Mice received 0, 0.796, 1.19,2.39 mg/kg of Chlorpyrifos-methyl orally every day for 1 month or 6 months. The results showed that thymus weight, macrophage function and acid α-naphthyl acetate esterase of T lymphocytes in mice were affected by 2.39 of chlorpyrifos-methyl. But no harmful effect were found in mice with exposure level at 1.19 or 0.796 mg/kg. It ls suggested that 1.19 mg/kg is maximal no-effect level of Chlorpyrifos-methyl in immunotoxicology.更多还原