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用Sulprostone治疗经期延期7天妇女的研究

Study of Sulprostone in Patients with Delay of Menstruation

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【作者】 钱丽娟刘贵敏曹小明

【Author】 Qian Lijuan,et al The Second Hospital of Tianjin Medical College

【机构】 天津医学院第二附属医院妇产科天津医学院第二附属医院同位素天津市计划生育研究所临床组

【摘要】 选择30例月经延期7天的妇女进行 Sulprostone 治疗,剂量为1.0mg,分二次肌注,中间间隔4小时。引产21例17例成功,其中13例(76.5%)引流产时间在30小时之内,4例(23.5%)超过30小时,引流产成功率为81%,有效3例占14.2%,失败1例;催经9例,均成功。二组副反应轻且可耐受,无严重并发症,血清β-hCG(放免测定法)和血红蛋白(沙利氏法)值在治疗前和治疗后1、3、8周进行测定。本文结果提示,对月经延期6~10天病人用 Sulprostone 催经止孕是一种简单、安全、有效和可接受的方法。

【Abstract】 Sulprostone was given intramuscularly in a schedule of 0.5mg at 4 hourly inter-val for 2 doses to 30 women at 37.9±0.33 days for menstrual inducing.Thirteen(76.5%)of twenty one pregnant women aborted within 30-hour observation period,four aborted more than 30 hours giving a success rate of 81.0%(17 cases).The effec-tive rate was 14.3%(3 cases),the failure rate 4.7%(1 case).All nine cases whowere amenorrhea admitted for provoking menstruation were successful with onlymild side-effects and were well tolerated.Plasma level of β-hCG and hemoglobinwere determined before and one,three and eight weeks after treatment.The studyindicates that the use of Sulprostone for pregnant or amenorrhea women with adelay in menstruation of 6~10 days is a simple,safe,effective and acceptable methodfor menstrual induction and early abortion.

  • 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1989年02期
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