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肺心病呼吸衰竭酸化与碱化药物的应用

The Application of Acidifier and Alkalizer in Cor Pulmonale Complicated with Respiratory Failure

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【作者】 陈真如

【Author】 Chen Zhen-ru. Section of Respiration, Affiliated Hospital, Nanjing Railway Medical College

【机构】 南京铁道医学院附院呼吸科 南京 210009

【摘要】 1985年12月至1987年6月肺心病并发呼吸衰竭49例(56次)住院资料,同步监测动脉血气与电解质,结合临床,分析酸碱失衡的类型,进行综合治疗,对降低死亡率起一定作用。对于酸中毒患者血pH<7.20时慎重补碱(5%NaHCO350ml/次),未发生碱中毒。呼酸并代碱仍占第二位,与应用利尿剂有关,常规补充氯化钾,酌情给盐酸精氨酸或醋氮酰胺,疗效较好。呼酸型三重酸碱失衡在肺心病急性发作期并非少见,经稳妥调整及病因治疗,亦可获较好疗效。

【Abstract】 The data of 49 cases(56 person-times) of cor pulmonale complicated with respiratory failure patients admitted from December 1985 to June 1987 were collected and analyzed. Through the records from the synchronous monitoring of arterial blood gas and electrolytes engaged, in combination with the clinical manifestations to analyze the types of acidbase imbalance, the patients were treated vigorously. By careful and skilful handling and concerted with combined treatment may give definite effect to deerease the mortality. In patients with acidosis(pH<7.20) supplementary alkaline should be handled with great care. About 50ml of 5% NaHCO3 solution a time, no alkalosis will happened. The respiratory acidosis combining with metabolic alkalosis is still ranked second. It is often related to the application of diuretics. Routine replenishment of KCl, arginine hydrochloride or acetazolamide according to the circumstances may show better effects. Respiratory acidosis type of triple acid-base imbalance is not rare in the acute attacks of cor pulmonale, and by safe and reliable adjustments of patients’ conditions, by treating patients with etiological therapeutics, better curative effects may be obtained too.

  • 【文献出处】 铁道医学 ,Railway Medical Journal , 编辑部邮箱 ,1989年02期
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