【摘要】 用羊红细胞花结抑制试验,测正常早孕血清、非妊娠血清、妊娠第7周正常绒毛组织培养液及蜕膜培养液的早孕因子活性。发现绒毛组织培养液和早孕血清提高花结抑制滴定度(P<0.05);蜕膜培养液和正常非妊娠血清对羊红细胞花结形成没有影响。正常绒毛组织可能是着床后妊娠血清早孕因子活性的来源之一。更多还原

【Abstract】 The increased susceptibility of T-lymphocytes to inhibition of E-rosette tbrmation by anti-thymocyte serum (ATS) is the means for the detection of Morton’s EPF (early pregnancy factor). Effect of villous tissue on E-rosette formation had not yet been reported. Using the rosette inhibition test (E-RIT), we descovered that villi from 7-wk normal placenta in vitro could release something to increase the rosette inhibition titre as EPF. Either early pregnant serum or the spent media (at least in first 48 h) of villous culture had significant effect on E-RIT (P<0.05). Decidua culture did not effect E-rosette formation in nonpregnant serum.更多还原