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激光终止家兔与小鼠早孕的效能

STUDIES ON TREMINATION OF EARLY PREGNANCY WITH LASER IN RABBITS AND RATS

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【作者】 丁爱华; 陈惠玲; 顾祖维; 连少辉; 崔可心; 郑怀美;

【Author】 Ding Aihua, Chen Huiling, Gu Zhuwei, Lian Shaohui, Cui Kexing, Zheng Huaimei(Gynecological and Obstetrical Hospital, Department of Gytotoxicology, School of Public Health,Department of Pathology, Faculty of Basic Medical Sciences, Shanghai Medical University,and Shanghai Institute of Physiology, Shanghai Institute of Biochemistry,Academice Sinica, Shanghai)

【机构】 上海医科大学妇产科医院; 中国科学院上海生理学研究所; 上海医科大学公共卫生学院细胞毒理室; 上海医科大学生物化学研究所; 上海医科大学基础医学部病理学教研室; 上海医科大学妇产科医院;

【摘要】 本文研究在家兔与小鼠上探索了激光终止早孕的效应,通过荧光分光光度计测定血卟啉衍生物(HPD)在胚胎组织中的荧光谱,证实HPD对胚胎组织有亲和力。将本文所选用的激光能量进一步观察了对遗传效应和卵巢功能的影响。

【Abstract】 This paper reports the effect of laser on terminating,early pregnancy in rabbits and mice,Results indicated that light sensitive hematoporphyrin derivative (HPD) In coordination with laser effects could induce blastocyst necrosis and complete absorption. By HPD fluorescence spectrum determination its affinity to embryonic tissue was shown to be about 4 times greater than to uterine tissue. These phenomena may explain the mechanism of early pregnancy termination by the light sensitive effect.Certain aspects of ovarian and genetic function were also studied. The irradi-ation power of the type of laser selected did not produce apparent ill effects.

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