【摘要】 用含2.569mg/kg赭曲霉毒素A (Ochratoxin A.以下称OA)的饲料,对40日龄左右的星波罗肉用鸡进行了饲喂试验试验鸡表现为精神沉郁,食欲不振、肠炎、贫血、极度消瘦等症状,于喂后13～18天,先后衰竭死亡,剖检发现肾、肝和肠道等都有明显的病理变化。经用高效液相色谱仪(HPLC)测定,肾脏,肝脏内OA的残留量分别为0.179mg/kg和0.1302mg kg。用从饲料中提纯的OA对孵化5日龄的鸡胚进行了气室内接种。根据接毒后记录的鸡胚死亡数和死亡率。计算出半数致死量为0.128μg。更多还原

【Abstract】 The feeding experiment of chicken was carried out with mixed-feed containing 2.569mg/kg Ochratoxin A （OA）. Thc chicken were discased in 2—3 days, and died after 13—18 days. The obvious pathological changes of livers, nephridia and intestines of dead chickens resulted from OA. The residue of OA in livers and nephridia was examined with HPLC. 0.179mg/kg and 0.1302mg/kg. respectively.Chicken embryos at 5 days were inoculated with OA extracted from mixed-feed. According to dead number and rate of chicken embryos. LD₅₀ of chicken embryos for ochratoxin A was 0.128μg.更多还原