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血清刀豆素A结合蛋白的检测及其临床意义

MEASUREMENT OF SERUM ConA-CONJUGATED PROTEIN AND ITS CLINICAL SIGNIFICANCE

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【作者】 魏群徐克成孟宪镛

【Author】 Wei Qun;Xu Kecheng;Meng Xianyong Research Section of Digestive Diseases, Affiliated Hospital, Nantong Medical College

【机构】 南通医学院附属医院消化研究室

【摘要】 将外源性凝集素ConA与血清中糖蛋白相结合,在电泳上可形成峰,根据峰的高低可测定血清中所谓ConA结合蛋白含量。正常人血清中ConA结合蛋白为95.16±14.54u/dl,慢性肝病时降低,肝细胞性肝癌时升高。本法简便,灵敏度高。初步显示测定血清中该种蛋白有助于肝病的鉴别诊断。

【Abstract】 Concanavalin-A(ConA), a kind of lectin, when combined with the serumglucoprotein, may form a peak in the electrophoresis. According to the heightof the peak, we are able to detect the amount of ConA-conjugated protein. Innormal individuals, the serum level is 95.16%±14.54u/dl, It decreases in chro-nic liver diseases and increases in hepatocellular carcinoma. This method isboth simple and sensitive. The assay for this kind of serum protein is prelimi-narily shown to be helpful in the differential diagnosis of liver diseases.

  • 【文献出处】 南通大学学报(医学版) ,Journal of Nantong University(Medical Sciences) , 编辑部邮箱 ,1989年02期
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