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硬膜外高渗氯化钠溶液术后镇痛的临床双盲研究
A DOUNLE-ELIND CLINICAL STUDY:EPIDURAL INJECTION WITH HYPERTONIC SALINE FOR POSTOPERATIVE ANALGESIA
【摘要】 为观察高渗盐水硬膜外注射术后镇痛效果,用双盲法对60例病人进行了研究。生理盐水对照级术后镇痛优良率为3.33%,镇痛有效率为10%,均需用镇痛药;高渗盐水组术后镇痛优良率为86.67%,有效率为96.67%,很少使用镇痛药。两组差别显著(P<0.05,P<0.01)。对其他感觉和运动功能无明显影响。高渗盐水组与吗啡组比较镇痛效果相同(P>0.05),副作用少(P<0.01)。说明硬膜外高渗氯化钠溶液是一种安全有效的镇痛方法,有较高推广应用价值。
【Abstract】 In order to study the pusr—operative analgesia effect of epidural injection with hypertonic saline,we observed 60 patients using double—blind method. The control group,the rate of effective post—operative analgesia is 3. 33%,all patients were injected with narcotics. The epidural hypertonic saline group,the rate of effective analgesia is 86. 67%,only 4 patients need narcotics. There are significient difference (P<0. 05, P<0. 01). The algesia effect of epidural hypertonic saline is equal to that of epidural morphine (P>0. 05). and the side effects are poorer(P<0. 01). The results indicate that epidural hypertonic saline is an effective and safe method for post—operative analgesia.
【Key words】 epidural; hypertonic saline; morphine; post-operative analgesia;
- 【文献出处】 潍坊医学院学报 ,Acta Academiae Medicinae Weifang , 编辑部邮箱 ,1989年03期
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