【摘要】 在碱性缩合剂存在下,由N-酰基噻唑啶-2-硫酮分别同丙二酸二乙酯及乙酰乙酸乙酯进行缩合,生成α-酰基丙二酸二乙酯(2_a～d),产率为67～78％;酰基乙酰乙酸乙酯（3_a,3_o）,产率为60～65％。更多还原

【Abstract】 On the basis of using 3-acylthiazolidine-2-thione as the acylating agent, a new method for the synthesis of c-aeylated malonie and acetoacetic esfers (2_a～d, 3_a, 3_e) is reported in this paper. These acylations were performed preferably in THF at room temperature for 24 h with NaH used as the condensing agent. The yield of 2_a～d is 67～78％, 3_a 65％ and 3_e 60％.更多还原