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自然流产夫妇的染色体分析(世界首报异常染色体核型3例)

Chromosome Study of the Married Couple with Spontaneous Abortions—3 abnormal karyotypes reported first in the world

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【作者】 杨长虹齐士云郭静德

【Author】 Yang Changhong Qi Shiyun(Family Planning Laboratory, The First Affiliated Hospital)

【机构】 哈尔滨医科大学一院计划生育研究室哈尔滨医科大学一院计划生育研究室

【摘要】 本文采用G显带技术对75对自然流产的夫妇进行了染色体分析,发现6例染色体异常核型,发生率为4%。其中46,XX,t(1;4);46,X,t(X;15)和46,XY,t(7;8)为世界首报异常染色体型。

【Abstract】 Chromosome banding studies were carried out on 75 couples with spontaneous abortions, among which three abnormal karyotypes were found first in the world. The paper discussed the relationship between spontaneous abortions and chromosomal aberrations and emphasesed that the couples with spontaneous abortions should be examined cytogenetically. The translocation carrier should be monitored by prenatal diagnosis which is imPortant to the improvement of the genetical quality of the Population.

【关键词】 染色体易位遗传
【Key words】 ChromosomeTranslocationHeredity
  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,1989年01期
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