【摘要】 Ph₃P/CF₃CCl₃与醛在室温下一锅反应生成三氟甲基取代的烯烃RCH=CClCF₃（3）。芳香醛及α,β-不饱和醛的反应显示高度立体选择性,给出Z式异构体。而饱和脂肪醛的反应立体选择性较低,Z与E式异构体的比例为2:1至3:1。反应可能是经由叶立德Ph₃P-CClCF₃的Wittig型反应。本工作表明,Pa₃P/CF₃CCl₃可以作为在十分温和的条件下向有机分子中引入=CClCF₃结构单元的方便试剂。更多还原

【Abstract】 An one pot synthesis of trifluoromethyl substituted olefins by reaction of Ph₃P/CF₃CCl₃ with aldehydes at room temperature was reported. The reactions with aromatioand α,β-unsaturated aliphatic aldehydes are highly stereoselective and give Z isomersof the olefins while the reactions with aliphatic aldehydes give Z and E isomers in 2:1to 3:1 ratios. The reaction might proceed via a phosphorus ylide Ph₃ P--CCICF₃ which wasgenerated in situ and then underwenta Wittig type of reaction with aldehydes. ThusPh₃P/CF₃CCl₃ may serve as a convenient reagent for transferring a CF₃CCl unit into anorganic molecule under very mild conditions.更多还原