【摘要】 合成了十五种新的3,6-二（二甲氨基）-二苯并碘六环稀土二柠檬酸配合物,其化学式为:[C₁₇H₂₀N₂I]₃[RE（C₆H₅O₇）₂]·xH₂O（RE=La-Nd,x=5;Sm-Tb,x=4;Dy-Lu,Y,x=3）。利用X射线粉末衍射、热重-差热,红外光谱、紫外光谱、摩尔电导等对这些配合物进行了表征。试验表明,镧配合物对L₇₇₁₂癌细胞DNA合成的抑制率（97.3％）明显高于其前体(C₁₇H₂₀N₂I⁺·HCOO^-,72.5％;Na₃[La（C₆H₅O₇）₂],-16.5％)。更多还原

【Abstract】 Fifteen new complexes of 3, 6-Bis（dimethylamino）-dibenzopyriodonium with rareearths citrate, having composition [C₁₇H₂₀N₂I]₃[RE（C₆H₅O₇）₂]·nH₂O（RE=La--Nd, n=5;RE=Sm--Tb,n=4; RE:=Dy--Lu, Y,n=3）, were synthesized. The complexes have beencharacterized by X-ray powder diffraction, TG-DTA, molar conductances, IR, UV and¹H NMR. Inhibiting effect of La complex on incorperation of ³H-TdR into DNA ofleukemia(L₇₇₁₂) cells in vitro was observed. The results show that La complex is moreeffective than its precursors.更多还原