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肺心病患者血浆血钠素和醛固酮测定

Determination of cardionatrin and aldosterone in the serum of the patients with pulmonary-heart disease

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【作者】 马秀风; 王和平; 苏天水; 宋朱斧; 钱翠萍; 马浩如; 孙鹏阁; 孙培宗;

【Author】 Ma Xiufeng et al Henan Institute of Medical Sciences

【机构】 河南省医学科学研究所; 河南医科大学第一附属医院内科; 河南医科大学第一附属医院内科;

【摘要】 本文对照组25例,肺心病心功能代偿组40例,心功能失代偿组25例,分别用放免法测定了血浆心钠素(ANF)和醛固酮(Ald),结果表明:①肺心病患者血浆ANF含量明显高于正常人,且随病情严重程度的发展ANF含量逐渐增高;②肺心病代偿组和失偿组血浆Ald含量明显低于正常人,且随病情严重程度的发展逐渐降低;③肺心病代偿组血浆ANF和Ald含量呈负相关,而失代偿组血浆ANF和Ald含量相关系数无明显性差异。并对ANF和Ald变化的机制进行了讨论。

【Abstract】 Cardionatrin and aldosterone in the serum of the patients with plulmonaryheartdisease were determined.The control group consisted of 25patients,the second group co-nsisted.of40 cases of pulmonary-heart disease at the wmpenscotion stage and the th-ird group 25cases of pulmonary-heart disease at the stage of heart failure.The resu-lts show that the ANF contents in the serum of the patients with pulmonary-heartdisease are signifioantly higher than those in the normal group,and the ANF con-tents in the serum increase with the development of the disease: and that the Aldcontents in the serum of the patients with pulmonary-heart disease at the stageof compensation and heart failure are lower than those in the normal group,and t-he Ald contents in the serum decrease with the development of the disenes.Theresults also soow that the ANF and Ald contents in the serum of the patients wi-th pulmonary-heart disease at the stage of heart failure showl negative relation,whareas in the heart failure group,there is no significant difference in the relati-voty constant ANF and Ald contents of serum. The mechnism of the change ofANF and Ald contents was disoussed.

【关键词】 肺心病; 心钠素; 醛固酮;
【Key words】 pulmonary-heart disease; cardionatrin; aldosterone;
  • 【被引频次】4
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