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大鼠等容心脏与左室压力-容积关系的实验方法
A METHOD FOR RAT ISOVOLUMIC HEART AND LEFT VENTRICULAR PRESSURE-VOLUME RELATION
【摘要】 采用左室内充液乳胶囊建立了一种离体大鼠等容左室实验方法。应用此方法可较方便和准确地测量左室压力和容积,从而可获得左室等容峰压-容积关系和舒张末期压力-容积关系。该方法稳定,获得的压力-容积关系具有良好的重现性,且可以反映心室收缩能力和心室可扩张性的变化。
【Abstract】 With an intraventricular water-filled balloon, a stable method of the rat isovolumic left ventricle was established. Left ventricular pressure and volume could be measured accuratly and conveniently, and highly reproducible peak isovolumic pressure-volume relation and end-diastolic pressure-volume relation, which serve as indexes of ventricular contractility and distensibility , respectively, were obtained.
【关键词】 等容心脏;
方法;
心室内囊;
压力-容积关系;
大鼠;
【Key words】 isovolumic heart; methods; intraventricular balloon; pressure-volume relation; rats;
【Key words】 isovolumic heart; methods; intraventricular balloon; pressure-volume relation; rats;
【基金】 国家自然科学基金
- 【文献出处】 湖南医科大学学报 , 编辑部邮箱 ,1989年03期
- 【被引频次】1
- 【下载频次】47