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大通湖农场影响HBV感染及转归的多因素分析
MULTIPLE VARIABLE ANALYSIS OF HBV INFECTION AND OUTCOME IN DATONG LAKE FARM
【摘要】 对785份血清标本检测 HBsAg、抗-HBs、抗-HBc、HBeAg、抗-HBe和HBV-DNA,同时收集有关危险因素资料,采用多因素分析。逐步回归分析结果提示:年龄与HBsAg滴度呈负相关(b2=-0.2672),其次影响HBsAg滴度的因素是全程HBV疫苗注射(b20=-0.1462)、性别(b1=0.0941)、针刺史(b1=0.0725)和既往肝炎史(b17=0.0695)。典型相关分析结果提示:反应感染状况的第一典型变量主要由综合指数(a=0.8414)所决定,反映影响因素的第二个典型变量主要由年龄(b=-0.8917)和HBV疫苗使用史(b=-0.4175)所决定。
【Abstract】 HBV serological markers and some related risk factors in a population of 785 were studed. Stepwise regression analysis indicated age has significant correlation with the titre of HBsAg ( b~=0. 2672) , other factors are the use of HBV vaccine (b~=0. 1462) , sex (b~= 0.0941) , history of injection or acupuncture (b~=0.0725) ; and history of hepatitis (b~= 0.0695), Canonical correlation analysis indicated the first canonical variable reflecting thd state of HBV infection is comprehensive index (a~= 0.8414), the second canonical variable are age (b~= -0.8917) and the use of HBV vaccine (b~= -0.4175) .
【Key words】 hepatits B virus; epidemiology; multiple variable analysis;
- 【文献出处】 湖南医科大学学报 , 编辑部邮箱 ,1989年02期
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