【摘要】 本文报道了²¹¹At-Te胶体对体外培养的人淋巴细胞Ag-NORs频率的影响。实验结果表明:α-辐射对经PHA刺激后已相继进入细胞增殖周期的淋巴细胞的Ag-NORs频率基本无影响;而对刚接受PHA刺激正在转化的淋巴细胞,低剂量幅照时,Ag-NORs频率明显升高,似乎具有刺激rRNA基因表达活性和增强转录作用;高剂量辐照时,Ag-NORs频率下降,具有一定抑制作用。更多还原

【Abstract】 The effect of 211At-tellurium colloid on the frequency of lymphocytes Ag-NORs culture in vitro was studied. The result showed that the alpha-radiation had no effect upon the frequency of Ag-NORs of lymphocytes which had been stimulated by PHA and entered in succession proliferation cycle of cell; but for the lymphocytes in transforming immediately being stimulated by PHA, in low irradiation does, the frequency of Ag-NORs was obviously increased, it seemed to be capable of stimulating the activation of rRNA gene and increasing transcription, while in high irradiation dose, it had some restraining effect.更多还原