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哌吡氮平和甲氰咪胍治疗十二指肠溃疡近期疗效的比较

Pirenzepine Versus Cimetidine in the Treatment of Duodenal Ulcer

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【作者】 佃雪辉; 郭桂英; 张文田; 李与为;

【Author】 Dian Xuehui Department of Internal Medicine

【机构】 贵阳医学院内科学教研室; 贵阳医学院内科学教研室;

【摘要】 本文对哌吡氮平与甲氰咪胍治疗十二指肠溃疡的近期疗效进行了比较。经4周治疗后,溃疡愈合率在哌吡氮平组为74.2%,甲氰咪胍组为68.2%,经统计学处理,两组疗效无明显差异(P>0.05)。本组观察结果认为哌吡氮平与甲氰咪胍对十二指肠溃疡均有良好的疗效,副作用较小。

【Abstract】 The purpose of this study was to compare the effects of pirenzepine and ci- metidine on the symptomatic relief and healing of duodenal ulcer. In 23 of 31 patients treated with pirenzepine and in 15 of 22 of those treated with cime- tidine, the ulcers had healed after 4 weeks of treatment The healing rate was 74.2% and 68.2% respectively. The difference was not statistically significant (P>0.05). The results show that pirenzepine is as effective as cimetidine for the treatment of quodenal uicer. There was no serious side-effect during the treatment.

【关键词】 哌吡氮平; 甲氰咪胍; 十二指肠溃疡;
【Key words】 pirenzepine; cimetidine; duodernal ulcer;
  • 【文献出处】 贵阳医学院学报 ,Journl of Guiyang Medical College , 编辑部邮箱 ,1989年01期
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