The infant mortality rates (IMR) is one of the important indices to re- flect population quality, but the IMR informations were in absence until 1981 in Guizhou. In this paper, based on the data the 1982 Population Census of Guizhou andthe one per thousand population samples survey in birth rates of Guizhou, in past years the IMR of our Province in different period was calculated by Feeney's technique. The results obtained werere liable, andfilled the sh ortage of the IMR data of Guizhou in this time.