【摘要】 本文报道在B超监护下经母腹作脐静脉穿刺取胎血33例,其中30例咨询孕妇作产前诊断,3例中孕引产。成功率为93.9％。孕龄与穿刺命中率,胎盘位置与穿刺命中率均不相关(P>0.05及P>0.05)。手术最佳时间是孕24周前后。手术并发症有胎心率变慢(或快),胎盘渗血,脐带渗血,脐血管空气栓塞等。但未发生死胎、流产、胎膜早破及感染。胎血的脆性X(fra(x))表达率较高,但脆性X并不复制。本法有可能成为fra(x)综合征的一种快速,可靠,安全,经济的产前诊断新方法。更多还原

【Abstract】 Percutaneous umbilical cord blood sampling was carried out in 30counselled woman for Prenatal diagnosis, from Nov 1988 to Jun 1089. The successrate was 93. 9%. Our results showed that there was no relationship betweenthe gestational week and the success puncture rat of the cord blood, and alsobetween the position of the placenta and the success puncture rate of thecord blood (P>0. 05), out we found that the optimum time for fetal bloodsampling is between 23--25 gestation weeks. The complications were fetalbradyeardia (Or fetal taehyeardia), cord bleeding, placenta blooding and airembolism, out there were no Fetal death, abortion premature rupture of themembrane or infection. Our results also showed that: 1, Fragile X in fetalblood sampling had a higher positive expression rate. 2, Fragile X does notduplicate. The possibility of using fetal blood sampling as a more convenientmethod in the prenatal diagnosis of the Fragile X syndrome suggested.更多还原