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苯妥英钠血药浓度监测的临床价值

CLINIC VALUE OF SERUM CONCENTRATION MONITORING OF SODIUM PHENYTOIN

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【作者】 苏长海李爱云高锡妮许春胜任全君谢昌华

【Author】 Su Changhai, et al Department of Neurology, Btnzhou Medical College, Shandong Province

【机构】 滨州医学院神经科滨州医学院神经科滨州医学院检验科

【摘要】 对61例癲痫患者测定了苯妥英钠血浓度。结果说明:1、相同的药物剂量可出现不同的血浓度;2、有些病人的血浓度虽然超过或低于有效范围,但也有较好的疗效;3、血药浓度越高,其毒副作用就越大。

【Abstract】 The serum concentration of sodium phenytoin was monitored for 61 cases of patients with epilepsy, the results showed as follows. 1、The same drug doses may induce different serum drug concentration. 2、Although serum drug concentration in some patients was higher or lower than effective limits, they also had better effects. 3、The higher serum drug concentration, the larger its toxicities and side-effects.

【关键词】 苯妥英钠药物监测
【Key words】 sob phenytoninserum concentration monitor
  • 【文献出处】 滨州医学院学报 ,Journal of Binzhou Medical College , 编辑部邮箱 ,1989年04期
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