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牙周病患者的免疫学观测

OBSERVATION ON THE DYNAMICS OF IMMUNITY IN PERIDENTAL DISEASE

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【作者】 李武修高美华邱世翠殷树勋刘爱荣李吉奎

【Author】 Lí Wuxíu, Department of Stomatology, Binzhou Medical College, Shandong Province

【机构】 滨州医学院口腔学教研室滨州医学院微生物学教研室滨州医学院口腔学教研室

【摘要】 本文采用单向琼脂扩散试验,简便PEG沉淀及淋巴细胞转化试验,对100例牙周病患者的免疫状态进行观测。实验结果表明牙周病患者血中及唾液中免疫球蛋白(Ig)含量、补体C3含量及淋转率明显降低,与对照组相比(P<0.01),有显著差异。而血循环免疫复合物(CIC)含量升高,与对照组相比(P<0.01),差异有高度显著地。由此表明,牙周病的发生可能与机体的免疫功能紊乱有关。

【Abstract】 In this article, simple agar diffusion test, PEG preciptation and lymphocyte blastogenesis test were applied to determine the dynamics of immunity in 100 patients with peridental disease. The results indicated that serum immunoglobnlin (s—Ig) C3 level and the rate of lymphocyte blastogenesis in patients with peridental disease were significantly decreased, as compared with those of the controlled group (P<0.01).But the circulating immune complex increased, the difference was highly significant (P<0.01).It was showed that peridental disease may be associated with a disorder in immune function.

【关键词】 牙周病免疫
【Key words】 peridental diseaseimmunity
  • 【文献出处】 滨州医学院学报 ,Journal of Binzhou Medical College , 编辑部邮箱 ,1989年02期
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