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自体软骨和软骨膜移植的初步实验观察

AN EXPERIMENTAL STUDY ON CARTILAGINOUS AND PERICHONDRIAL AUTOGRAFT

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【作者】 鲍卫汉朱洪荫朱丽音赵惠勇王惠

【Author】 Research Center of Plastic Surgery, the Third Hospital Bao Weihan, et al

【机构】 北京医科大学第三医院成型外科研究中心北京医科大学病理解剖教研室北京医科大学第三医院成型外科研究中心

【摘要】 经过35只成年家兔和12只幼兔的移植物观察,其中仅有一块耳软骨呈现吸收,其余经肉眼检查未见明显改变,但光镜下有的软骨出现软骨细胞增生及软骨灶状钙化、骨化、核退变、基质嗜硷性变等病理改变。幼兔的耳软骨移植后个别的有增大。29.4%的兔耳软骨膜有形成软骨——弹性软骨的能力。

【Abstract】 Thirty two pieces of ear cartilage, 12 pieces of rib cartilage from 18 adult rabbits were implanted subcutaneously, intramuscularly. It was noticed after 6 months that most of the grafts were unchanged in size, except one piece of ear cartilage being absorbed to a great extent postoperatively. Proliferation of chondrocytes, focal calification and ossification and degeneration of nuclei could be seen in some grafts under microscope, These changes were not related to positions of implantation.Twenty-four ear cartilage grafts from twelve baby rabbits were transplanted. Grafts in two rabbits increased in size and became thickened. Proliferation of perichond-rium and neochondrocytes appeared in another three, there was no sign of growth in the rest,Perichondium graft is able to form cartilage but not in all cases. Elastic cartilage formed in five out of seventeen rabbits’ ear perichondium grafts (that is, 29.4%) in this study.

【关键词】 自体移植软骨软骨膜
【Key words】 Transplantationautologous Cartilage Perichondrium
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