【摘要】 本文报道应用超微结构体视学定量分析方法观察81例脾虚患者胃粘膜胆碱能运动神经终末的变化,并结合血cAMP、cGMP含量的验定,探讨了形态改变与机能之间的联系。结果表明,脾虚气滞组患者胆碱能神经终末内乙酰胆碱递质小泡显著多于脾胃气虚组(p<0.001),血cGMP含量明显高于脾胃气虚组(p<0.002)和正常对照组(p<0.02);血cAMP/cGMP比值则明显低于其它两组(P<0.005—0.001);此结果从超微结构水平提供了脾虚气滞型患者胃肠胆碱能神经功能偏亢的形态学依据,从而提示胆碱能神经偏亢可能为此型患者发病的一个重要机制。更多还原

【Abstract】 In this paper, gastric specimens of spleen and stomach Qi deficiencyand spleen defieieney with Qi stagnation obtained from 81 patients with spleen deficiency syndrome (SD during fibrogastroseopieal mucosal biopsy were observed with the electron microseope. The number of Ach,vesicles in the eholinergic nerve was analysed.This study found the difference of the number of Ach.vesieles and the contents of cAMP.cGMP in serum possessed statistical significance between the types of SD syndrome(p<0.02--0.001).The results suggested:①the difference is due to the various degrees of change of the autonomic nerve system in the types of SD syndrome,②the hyperfunction of cholinergie nerous function is an important cause of spleen deficiency with Qi stagnation.更多还原