【摘要】 对38例住院输血病人(血液病18例,上消化道出血20例)进行了HLA抗体的观察。结果阳性11例(29%),其阳性率与受血次数密切相关。输血反应11例中检出HLA抗体9例(81.8%),输血反应严重者抗体强度高。7例HLA抗体阳性者随输血减少抗体阴转且输血反应不再出现。2例HLA抗体(++++)输血反应严重者多次接受红细胞输注无不良反应。更多还原

【Abstract】 Thirty-eight patients who received transfusions in our hospital were tested for anti-his(?)ocompatability antigen (HLA) The group consisted of 18 cases of hematolog(?)c disease and 20 cases of upper gastrointestinal bleeding. Eleven patients developed HLA antibodies after transfusion. The incidence of anti-HLA was closely related to the number of transfusions. Of the 11 cases of nonhemolytic transfusion reaction (NHTP), nine (81.8%) had anti-HLA in the sera Severe NHTR occurred in patients whose antibody levels were much higher. There were seven cases in which antibodies disappeared gradually as the number of transfusions decreased and NHTR did not recur. Two patients with strong anti-HLA and severe NHTR received transfusions of red blood cells on several occasions later with no reaction.更多还原