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青光眼旁中心区光阈值及短期波动的初步探讨

A study on light threshold and short-tem fluctuation of glaucoma

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【作者】 陈晓明吴振中蒋幼芹李毅

【Author】 Chen Xiaoming, et al Department of Ophthalmology, znd Affiliated Hospital, Hunan Medical College

【机构】 湖南医学院眼病研究室湖南医学院第二附属医院眼科湖南医学院第二附属医院眼科

【摘要】 <正> 青光眼视野改变的发生和发展是一渐进性过程。近年来,国外许多学者致力于自动定量视野计光阈值及其波动的研究,以期在青光眼视野缺损出现前,发现有意义的最早期视功能改变。Hart和Bocker(1582)提出,青光眼最早期的视野改变不是相对暗点,而是光阈值的升高。Flammer(1084)报道,青光眼阈值的波动明显大于正常人,而且,这种波动的增加是将出现视野缺损的先兆表现,我们采用Humphrey自动视野计对一组青光眼患者进行光阈值定量检查,以探讨光阈值改变及其短期波动在青光眼早期诊断中的意义。

【Abstract】 Using automatic perimetrey (Humphrey Field Analyzer. model-610) We determined the static light threshold and short-term fluctuationof four primary points at 15° from fixation of 52 eyes with ear-ly glaucoma, but normal central visual field pualitatively (GoldmannPerimeter), and comparedt he result with 47 age-matching controls Thestudy showed there are highly significant differences in the mean threshld level and short-term fluctuation between the two groups (P<0.001).we also found these components are positive correlated with verticalC/D, The study suggested that increaseo f light threshold and short-term fluctuaion be the earliest glaucomatous visual field damages.

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